Boston Adolescent Neuroimaging of Depression & Anxiety

Launched in 2015, the BANDA study is among the first of several projects funded by the National Institute of Health (NIH) to study a disease population using data collection protocols from The Human Connectome Project, a multi-institutional project seeking to build a comprehensive map of neural connections in the human brain. Headed by researchers at the McGovern Institute for Brain Research at the Massachusetts Institute of Technology, and in collaboration with research teams at McLean Hospital, Boston University, and Mass General Hospital, this study aims to probe adolescent depression and anxiety at multiple levels of analysis, collecting MRI and clinical/behavioral data from adolescents with depression or anxiety disorders, comparing them with healthy controls, and utilizing algorithms and brain imaging software to map out relevant circuits in the brain. The goal is to determine whether we can find reliable biomarkers for these disorders which can be used to more accurately predict clinical outcomes.

More info can be found at


  • Siless, V., Hubbard, N. A., Jones, R., Wang, J., Lo, N., Bauer, C., Goncalves, M., Frosch, I., Norton, D., Vergara, G., Conroy, K., De Souza, F. V., Rosso, I. M., Wickham, A. H., Cosby, E. A., Pinaire, M., Hirshfeld-Becker, D., Pizzagalli, D. A., Henin, A., Hofmann, S. G., … Yendiki, A. (2020). Image acquisition and quality assurance in the Boston Adolescent Neuroimaging of Depression and Anxiety study. NeuroImage. Clinical, 26, 102242.

  • Hubbard, N. A., Siless, V., Frosch, I. R., Goncalves, M., Lo, N., Wang, J., Bauer, C., Conroy, K., Cosby, E., Hay, A., Jones, R., Pinaire, M., Vaz De Souza, F., Vergara, G., Ghosh, S., Henin, A., Hirshfeld-Becker, D. R., Hofmann, S. G., Rosso, I. M., Auerbach, R. P., … Whitfield-Gabrieli, S. (2020). Brain function and clinical characterization in the Boston adolescent neuroimaging of depression and anxiety study. NeuroImage. Clinical, 27, 102240.


from left to right
(Top) Diego Pizzagalli, John Gabrieli, Larry Wald, Aude Henin
(Bottom) Bruce Rosen, Anastasia Yendiki, Susan Whitfield-Gabrieli, Stefan Hofmann, Randy Auerbach, Satra Ghosh